28.05.2024: Hanjo HELLMANN (Washington State University): Controlled protein stability to regulate abiotic stress tolerance and development in plants , HS 32.01, Institut für Biologie, Bereich Pflanzenwissenschaften, Holteigasse 6, 17.00 Uhr
Plant stress and development are dynamically driven by the intricate regulation of protein instability, crucial for survival and growth. Environmental stressors like drought, salinity, or extreme temperatures cause misfolding and damage to proteins. To combat this, plants deploy quality control systems such as molecular chaperones and the ubiquitin-proteasome system (UPS), which meticulously tag and degrade faulty proteins, preventing toxic aggregates.
The UPS is a highly conserved eukaryotic pathways that acts as a central regulatory tool, ensuring rapid adaptation by managing the proteome under stress. Simultaneously, stress-responsive proteins and transcriptional regulators are finely tuned, enhancing their stability and efficacy. This proteostasis is not only vital for stress response but also for developmental processes like cell cycle regulation, hormone signaling, and differentiation.
The presentation is focusing on specific steps within the UPS, and how their modulation can be used to regulate specific stress and developmental traits in plants.